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Examples ofrenin
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Changes in therenin-angiotensin-aldosterone axis with age are considered below.
From theCambridge English Corpus
Effect of aging onreninactivity and aldosterone excretion.
From theCambridge English Corpus
Effect of ageing onreninactivity and aldosterone excretion.
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Declining circulatingreninand aldosterone levels lead to saltwasting and reduced blood volume.
From theCambridge English Corpus
Diuretic therapy, the mainstay of treatment in chronic heart failure, leads to increased activation of therenin-angiotensin-aldosterone system.
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Sympathetic stimulation plays a significant part in activation of therenin-angiotensin-aldosterone system, exacerbating the tendency to retain salt and water.
From theCambridge English Corpus
This loss of responsiveness is not present in therenin-angiotensin-aldosterone axis where the reflex is well-maintained into old age.
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Role ofrenin-angiotensin system in response to hemorrhage in fetal sheep.
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Plasmareninactivity and aldosterone levels are normal or increased.
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Lloyd et al21 did not find significant changes in the activity of eitherreninmeasured in the plasma, or aldosterone.
From theCambridge English Corpus
Activation of the sympathetic nervous system,reninrelease from the kidney and antidiuretic hormone release from the pituitary each add to salt and water retention seen in heart failure.
From theCambridge English Corpus
Indirectly, secretion is also promoted by activation of therenin-angiotensin-aldosterone axis by a diminished effective arterial blood volume such as occurs in hypovolaemia, cirrhosis or congestive cardiac failure.
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Several authors have proposed that the primary event is expansion of the intravascular volume35 with chronic suppression of therenin-aldosterone system due to resetting of the sensors.
From theCambridge English Corpus
Thereninmolecule contains both hydrophobic and hydrophilic amino acids.
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This example is from Wikipedia and may be reused under a CC BY-SA license.Diuretic therapy for heart failure29 was pivotal until the role of the angiotensin-reninsystem was fully understood and able to be modified pharmacologically.
From theCambridge English Corpus
When blood volume is low, juxtaglomerular cells in the kidneys activate their prorenin and secreterenindirectly into circulation.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.Another is renal artery stenosis, in which the reduced blood supply across the juxtaglomerular apparatus stimulates the production ofrenin.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
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This example is from Wikipedia and may be reused under a CC BY-SA license.Hopes of breakthrough appeared in 1982 when development of the second generationrenininhibitors began.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
- rack up
- rail at
- rail in
- rail off
- rain cats and dogs
- rain in
- rain or shine
- rain out
- rainy day
- raise the roof
- raise（one's）eyebrows
- rather than
- rattle/reel off
- rattle through
- rave about
- reach for
- read between the lines
- read into
- read out of
- read sb．'s mind
- read up
- ready for
- reckon on
- reckon with
- reconciled to