screwsbup
—phrasal verbwithscrewverbuk/skruː/us/skruː/
informalWhenbadexperiencesorpeoplescrewyou up, they make youworriedandunhappyordamageyourpersonality.
使（某人）焦虑不安；令（某人）很难过；使（某人）精神崩溃
It reallyscrewedhim up when hesawhisfriendgetkilled.看到自己的朋友遇难，他伤心欲绝。