单词 | penetrance |
释义 | BETA Examples ofpenetranceDictionary> Examples ofpenetrance penetranceisn’t in the Cambridge Dictionary yet. You can help! Add a definition Ignoring the mixture distribution of the unobserved genotype, they were able to estimate and test the diseasepenetrancedifference between alternative genotypes. From theCambridge English Corpus When some people with that genotype never manifest the condition over a normal life span,penetranceis incomplete or low. From theCambridge English Corpus There is evidence for incompletepenetranceof this disorder. From theCambridge English Corpus By appropriate choice ofpenetrancevalues, an arbitrary mode of inheritance can be specified including additive, dominant, recessive, and others. From theCambridge English Corpus They treated the probabilities of disease incidence conditional on genotypes (called thepenetrance) as parameters of interest. From theCambridge English Corpus Thepenetranceof the disease gene is 75%. From theCambridge English Corpus Even genetic disorders of highpenetranceare not manifested equivalently across individuals. From theCambridge English Corpus Conversely, the actual phenotypic disease of phenylketonuria showed increasingly incompletepenetrancewith widespread introduction of low phenylalanine diet. From theCambridge English Corpus Furthermore, for infected pregnant mice, transmission occurs to at least one foetus in 100 % of cases while variablepenetranceof congenital infection is observed. From theCambridge English Corpus Note thatpenetranceand expressivity are aggregate variables which represent information that can not be assigned back to individuals. From theCambridge English Corpus Three mathematical components form the basis of complex segregation analysis : thepenetrancefunction, the gene frequency distribution and the transmission probabilities distribution. From theCambridge English Corpus This observation highlights the importance of consideration of the genetic background when studying traits with variablepenetrance. From theCambridge English Corpus The author explains the genetics of ' complex illnesses ', involving multiple genes, as well as variablepenetranceand variable expressivity. From theCambridge English Corpus It is extremely difficult to distinguish between expectations on a hypothesis due to autosomal dominance with lowpenetranceand one invoking multifactorial predisposition. From theCambridge English Corpus We derived the non-centrality parameters in a very general genetic model, in which thepenetranceof each of the three genotypes is defined. From theCambridge English Corpus In the latter case, sporadic autism is possibly caused by a spontaneous mutation with highpenetrancein males and poorpenetrancein females. From theCambridge English Corpus Familial occurrence is widely recognized as an autosomal dominant trait with incompletepenetranceand variable expression. From theCambridge English Corpus These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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