Four of these unique predictors were individual symptoms present during the identified depressive episode : sad mood, weight loss,hypersomniaand fatigue.
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The adverse events observed most frequently in patients treated with olanzapine relative to comparators were related to somnolence (somnolence, fatigue, orhypersomnia) and weight gain (weight gain, or increased appetite).
From theCambridge English Corpus
These behavioural changes include fever, experience of weakness, fatigue,hypersomnia, depressed activity, decreased appetite and loss of interest in social activities, and result in a state of general malaise.
From theCambridge English Corpus
Although anti-depressants, in general, have not been found to be helpful for treatment of idiopathichypersomnia, bupropion specifically is known to have wake-promoting effects.
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Upper airway resistance syndrome is a clinical variant of sleep apnea that can also causehypersomnia.
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Paraneoplastic syndromes can also cause insomnia,hypersomnia, and parasomnias.
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The disorder is characterized by episodic periods ofhypersomniaand lethargy.
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However, current research is raising the possibility of several other potential medication options for idiopathichypersomnia.
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Sleep apnea is the most frequent cause of secondaryhypersomnia, affecting up to 4% of middle-aged adults, mostly men.
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Many medications can also lead to secondaryhypersomnia.
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However, more than one type ofhypersomniacan coexist in a single patient.
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Behaviorally induced insufficient sleep syndrome must also be considered in the differential diagnosis of secondaryhypersomnia.
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Patients with idiopathichypersomniadisplay these symptoms continually for months or years.
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Idiopathichypersomniahas long been considered a rare disease and was believed to be 10 times less frequent than narcolepsy.
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Often it's the result of sleep deprivation, mental fatigue, depression, sleep apnea, hypoxia, narcolepsy, or idiopathichypersomnia.
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