kinase domain
collocation in Englishmeaningsofdomain
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domain
noun[C]
uk/dəˈmeɪn/us/doʊˈmeɪn/
an area of interest or an area over which a person ...
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(Definition ofdomainfrom theCambridge English Dictionary© Cambridge University Press)
Examplesofkinase domain
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
Thekinasedomainis in equilibrium between an 'open, accessible ' state, subject to phosphorylation, and a 'closed, competent' state, able to perform catalysis.
From theCambridge English Corpus
Within the tyrosinekinasedomain, further characteristic motifs can be found.
From theCambridge English Corpus
W mutant mice with mild or severe developmental defects contain distinct point mutations in thekinasedomainof the c-kit receptor.
From theCambridge English Corpus
The net result is the phosphorylation of substrate molecules, either through akinasedomainon the receptor itself or through activation of a protein kinase through second messenger pathways.
From theCambridge English Corpus
Thekinasedomain, while important for necroptotic (programmed necrotic) functions, it appears dispensable for other lethal, as well as pro-survival roles.
From
Wikipedia
A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosinekinasedomain.
From
Wikipedia
These receptors are known as dual-specificity kinases because their cytoplasmickinasedomainhas weak tyrosine kinase activity but strong serine/threonine kinase activity.
From
Wikipedia
When src is phosphorylated on a particular tyrosine, it folds on itself, and thus masks its ownkinasedomain, and is thus turned off.
From
Wikipedia
This, in turn, causes a conformational change in the insulin receptor that activates thekinasedomain residing on the intracellular portion of the beta subunits.
From
Wikipedia
The alpha subunits have the catalytickinasedomain.
From
Wikipedia
The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threoninekinasedomainrequired for signaling.
From
Wikipedia
It lacks an intracellular serine/threonine proteinkinasedomainand hence is a pseudoreceptor.
From
Wikipedia
That can mimic the activation loop phosphorylation and - by jumping all control steps at normal activation - immediately render thekinasedomainfully active.
From
Wikipedia
A full-length representative protein consists of an extracellular region, composed of three immunoglobulin domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosinekinasedomain.
From
Wikipedia
The encoded protein contains an amino-terminalkinasedomain, and a carboxy-terminal regulatory domain that mediates homodimerization.
From
Wikipedia
This member contains a nuclear targeting signal sequence, a proteinkinasedomain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat.
From
Wikipedia
The formation of such complex brings the two intracellular domains in close proximity to each other, eliciting initial trans-phosphorylation of eachkinasedomain.
From
Wikipedia
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
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