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Examples oflagging strand
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However, there is a problem going in the other direction on thelaggingstrand.
From
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This example is from Wikipedia and may be reused under a CC BY-SA license.Because of its orientation, replication of thelaggingstrandis more complicated than that of the leading strand.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.Consider the following: the helicase continuously unwinds the parental duplex, but thelaggingstrandmust be polymerised in the opposite direction.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.Primase also acts as a halting mechanism to prevent the leading strand from outpacing thelaggingstrand by halting the progression of the replication fork.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.On the leading strand this route is continuous, but on thelaggingstrandit is discontinuous.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.Thelaggingstrandis synthesized in short, separated segments.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.When this is complete, a single nick on the leading strand and several nicks on thelaggingstrandcan be found.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.Electron microscopy studies indicate that nucleosome loading on thelaggingstrandoccurs very close to the site of synthesis.
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Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.Since replication occurs in opposite directions at opposite ends of parent chromosomes, each strand is alaggingstrandat one end.
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Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.The priming event on thelaggingstrandestablishes a replication fork.
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Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.At this point, thelaggingstrandreplicative polymerase associates with the clamp and primer in order to start polymerisation.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.There is a richness of guanine over cytosine and thymine over adenine in the leading strand and vice versa for thelaggingstrand.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.Duringlaggingstrandsynthesis, the replicative polymerase sends thelaggingstrandback toward the replication fork.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.Furthermore, the time used for replication between the two strands varies and may lead to asymmetric mutational pressure between leading andlaggingstrand.
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Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.This makes the speed oflaggingstrandsynthesis much lower than that of the leading strand.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.This means that, while polymerisation of the leading strand proceeds, polymerisation of the laggingstrandonly occurs after enough of thelaggingstrandhas been unwound by the helicase.
FromThis example is from Wikipedia and may be reused under a CC BY-SA license.
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.