major obstacle
collocation in Englishmeaningsofmajorandobstacle
These words are often used together. Click on the links below to explore the meanings. Or,see other collocations withobstacle.
major
adjective
uk/ˈmeɪ.dʒər/us/ˈmeɪ.dʒɚ/
more important, bigger, or more serious than others of the ...
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obstacle
noun[C]
uk/ˈɒb.stə.kəl/us/ˈɑːb.stə.kəl/
something that blocks you so that movement, going forward, or action is prevented or made ...
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(Definition ofmajorandobstaclefrom theCambridge English Dictionary© Cambridge University Press)
Examplesofmajor obstacle
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
Themajorobstaclein learning inverse kinematics lies in the problem that the inverse kinematics of a redundant kinematic chain has infinite solutions.
From theCambridge English Corpus
Themajorobstacleto this approach is the design of vectors and strategies that will lead to tumourspecific activation of the prodrugs.
From theCambridge English Corpus
The sheer number and variety of food products, and complex combinations of ingredients in many processed foods, seem amajorobstacleto any would-be regulator.
From theCambridge English Corpus
Such a small sign inventory also constitutes amajorobstacleto decipherment.
From theCambridge English Corpus
Cook considers the canon amajorobstaclefor looking at music from a wider perspective.
From theCambridge English Corpus
This constitutes amajorobstacleto the ongoing peace negotiations.
From theCambridge English Corpus
Although this might be possible on occasions, this will present amajorobstaclefor the implementation of the policy.
From theCambridge English Corpus
What once seemed like amajorobstaclecan become a mere footnote in a person's life.
From theCambridge English Corpus
Imperfect information is amajorobstacleto textbook supply and demand.
From theCambridge English Corpus
However, extracellular spaces in the brain are very narrow and represent amajorobstaclethat requires cells to dynamically regulate their volume.
From theCambridge English Corpus
Amajorobstaclefor this approach, however, is the fact that very fine-grained semantic distinctions can be made in the update-language.
From theCambridge English Corpus
Informal repression has proved amajorobstacleto prospects for democratisation.
From theCambridge English Corpus
Amajorobstaclein this approach would be the necessity for synchronisation of the cell cycle.
From theCambridge English Corpus
The mismatch between the operational semantics of the lambda calculus and the actual behavior of the prototypical implementation is amajorobstaclefor compiler writers.
From theCambridge English Corpus
However, amajorobstacleto the commercial development of these nematode parasites as biological control agents is their apparent specificity and host-range.
From theCambridge English Corpus
There's amajorobstacle, however, to these subjects fully entering opera, as the very vocabulary of my remarks probably reveals.
From theCambridge English Corpus
A fundamental tenet of family history is that in the past high mortality was amajorobstacleto household complexity.
From theCambridge English Corpus
The lack of available finance initially posed amajorobstacleto creating a statutory marketing agency.
From theCambridge English Corpus
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
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