Of the nine that coroners had finished investigating, two were caused directly bymephedrone.
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In addition to its stimulant effects,mephedroneproduces side effects, of which teeth grinding is the most common.
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Mephedroneadministration caused about a 500% increase in dopamine, and about a 950% increase in serotonin.
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Of those who had already usedmephedroneprior to the ban, 75% had continued to use it after the ban.
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Firstly, dealers knew there was still demand formephedrone, but were aware the supplies may be exhausted in the future.
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They concluded more experimental research is needed to investigate the toxicity ofmephedrone.
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Due to its similarity tomephedrone, it is thought to be a stimulant and entactogen drug of the phenethylamine, amphetamine, and cathinone chemical classes.
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It became available online in 2010 and has been sold as replacement for 4-methylmethcathinone (mephedrone).
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I fear that the only message that will be sent by the hasty decision onmephedroneis that the drug laws deserve no respect.
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In 2010, as its use became more prevalent, many countries passed legislation prohibitingmephedrone.
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In another case, a 19-year-old male was admitted to hospital suffering from inflammation of the heart, 20 hours after taking one gram ofmephedrone.
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Because 4-methylephedrine can be obtained in a specific enantiomeric form,mephedroneconsisting of only one enantiomer can be produced.
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Mephedronewas first synthesized in 1929, but did not become widely known until it was rediscovered in 2003.
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This is the enzyme involved in the processing of amphetamines of the cathinone group, includingmephedroneand khat.
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Around 50% of users reported at least one negative effect associated with the use ofmephedrone, of which teeth grinding is the most common.
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