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单词 misfolding
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Examples ofmisfolding

Dictionary> Examples ofmisfolding
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Misfoldingerrors and the barriers that they impose are probabilistic, not intrinsically coded into the pathway.
From theCambridge English Corpus
A potential therapy for proteinmisfoldingis to correct defective protein folding and trafficking using pharmacological chaperones.
From theCambridge English Corpus
Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in proteinmisfoldingdiseases.
From theCambridge English Corpus
First, inhibition of earlymisfoldingprecludes a build-up of toxic oligomers or protofibrils.
From theCambridge English Corpus
Protein aggregation and aggregate toxicity : new insights into protein folding,misfoldingdiseases and biological evolution.
From theCambridge English Corpus
Protein aggregation and aggregate toxicity: new insights into protein folding,misfoldingdiseases and biological evolution.
From theCambridge English Corpus
A high priority will be to assess whether drug candidates prevent the formation of oligomers, protofibrils or fibrils, and whether they reduce toxicity in animal models ofmisfoldingdiseases.
From theCambridge English Corpus
Together, these findings underscore the important role of oxidative stress in various protein-misfoldingdisorders, and they suggest that antioxidants are reasonable therapeutic candidates in the treatment of these diseases.
From theCambridge English Corpus
Proteinmisfolding: optional barriers, misfolded intermediates, and pathway heterogeneity.
From theCambridge English Corpus
Two alternativemisfoldinghypotheses instead suggest that either tau protein or amyloid beta initiates the cascade.
From
Wikipedia
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Several diseases are characterised by proteinmisfoldingand aggregation.
From theCambridge English Corpus
The mutation occurred in the gene encoding rhodopsin and induced an amino acid substitution known to result inmisfoldingof the protein.
From theCambridge English Corpus

These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.

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