Tay-Sachs Disease
noun[U]
medicalspecializeduk/teɪˈsæks dɪˌziːz/us/ˈteɪˌsæks dɪˌziːz/(abbreviationTD);(abbreviationTSD);(B variant GM2 gangliosidosis)ageneticdiseasein which thebodyisunableto getridof afattysubstancecalled ganglioside so that itbuildsup in thebrain,causingthenervestostopworkingproperlyandeventuallyleadingtodeath, usually before theageof three:
家族黑蒙性白痴病For achildto have Tay-Sachs Disease, bothparentsmust have thedefectivegeneresponsible.只有当父母都携带有缺陷的相关基因时，他们的孩子才会罹患家族黑蒙性白痴病。