variable region

collocation in English

meaningsofvariableandregion

These words are often used together. Click on the links below to explore the meanings. Or,see other collocations withregion.
variable
adjective
uk
/ˈveə.ri.ə.bəl/us
/ˈver.i.ə.bəl/
likely to ...
See more atvariable
region
noun[C]
uk
/ˈriː.dʒən/us
/ˈriː.dʒən/
a particular area or part of the world, or any of the large official areas into which a country ...
See more atregion

(Definition ofvariableandregionfrom theCambridge English Dictionary© Cambridge University Press)

Examplesofvariable region

These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
The primer was complementary to thevariableregionof the second repeat, but it annealed with lower specificity also to the other 5 repeats.
From theCambridge English Corpus
Oligonucleotides were selected from constant regions of the minicircle in order to anneal sites flanking thevariableregion.
From theCambridge English Corpus
Mapping the structural differences between the alpha subunit isoforms identifies avariableregionof the protein involved in receptor interactions.
From theCambridge English Corpus
It is believed that thisvariableregionis a pathogenicity island that contains genes that are essential for virulence.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
Since thevariableregiondoes not change, class switching does not affect antigen specificity.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
Each heavy chain has two regions, the "constant region" and the "variableregion".
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
The antigenic determinant or epitope is recognized by the paratope of antibody, situated at thevariableregionof the polypeptide chain.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
Thevariableregionin turn has hypervariable regions which are unique amino acid sequences in each antibody.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
Thevariableregionof each immunoglobulin heavy or light chain is encoded in several piecesknown as gene segments (subgenes).
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
He also defined the paratope to be that part of an antibodyvariableregionthat binds to an antigen.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
They define the surface and properties of thevariableregion, determining the antigen specificity and therefore the idio tope of the molecule.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
In some cases it can be the actual antigen-binding site, and in some cases it may comprisevariableregion sequences outside of the antigen-binding site on the antibody itself.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
Thus, when studying the origin of antigen specificity, only the variable regions need to be sequenced.
From theCambridge English Corpus
This protocol is possible because an antibody consists of two parts, avariableregion(which recognizes the antigen) and constant region (which makes up the structure of the antibody molecule).
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
It also led to the identification of a core set of sequences apparently required for virus function and variable regions responsible for the differences between viruses.
From theCambridge English Corpus
Hyper variable regions may change in both intra and interspecies transmission.
From the
Hansard archive
Example from the Hansard archive. Contains Parliamentary information licensed under theOpen Parliament Licence v3.0
During class switching, the constant region of the immunoglobulin heavy chain changes but the variable regions, and therefore antigenic specificity, stay the same.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
Humanized antibodies are almost completely human; only the complementarity determining regions of the variable regions are derived from murine antibodies.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
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See other collocations withregion