Transcriptional targeting modalities in breast cancer gene therapy usingadenovirusvectors controlled by alpha-lactalbumin promoter.From theCambridge English Corpus
Although animals were injected with the same amount of recombinantadenovirus, the level of expression detected depended on the individual promoter activity.From theCambridge English Corpus
Becauseadenovirusis a commonly occurring virus, most humans are pre-primed to at least one specific serotype.From theCambridge English Corpus
Repeated administration of a therapeuticadenovirusmust be performed, which could result in an inflammatory response in the patient.From theCambridge English Corpus
Separating fact from fiction: assessing the potential of modifiedadenovirusvectors for use in human gene therapy.From theCambridge English Corpus
The other viral outbreaks (rotavirus andadenovirus) were all transmitted by person-toperson contact.From theCambridge English Corpus
Image reconstruction reveals the complex molecular organisation ofadenovirus.From theCambridge English Corpus
Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice.From theCambridge English Corpus
The ferritin transgenes were delivered using a replicative-deficientadenovirus.From theCambridge English Corpus
Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.From theCambridge English Corpus
An optimal animal model of the immunological challenges associated with human clinical trials for gene therapy would involve immunization with a wild-type, replicating, humanadenovirus.From theCambridge English Corpus
Replication-defective recombinant adenoviruses are the second most commonly used viral vectors in clinical trials today.From theCambridge English Corpus
First-generationadenoviruscan be engineered with powerful promoters to drive expression of therapeutic transgenes.From theCambridge English Corpus
Nonintegrating viruses, like adenoviruses, have the disadvantage that they remain episomal and can be lost during cell division.From theCambridge English Corpus
For the systemic immunization to eliminate transgene expression from the brain, >16107 infectious units (iu) ofadenovirusneed to be used as immunogen.From theCambridge English Corpus
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