mitochondrial dysfunction

collocation in English

meaningsofmitochondrialanddysfunction

These words are often used together. Click on the links below to explore the meanings. Or,see other collocations withdysfunction.
mitochondrial
adjective
uk
/ˌmaɪ.təˈkɒn.dri.əl/us
/ˌmaɪ.t̬əˈkɑːn.dri.əl/
relating to the small parts of most living cells that contain DNA ...
See more atmitochondrial
dysfunction
noun[C]
uk
/dɪsˈfʌŋk.ʃən/us
/dɪsˈfʌŋk.ʃən/
a problem or fault in a part of the body or ...
See more atdysfunction

(Definition ofmitochondrialanddysfunctionfrom theCambridge English Dictionary© Cambridge University Press)

Examplesofmitochondrial dysfunction

These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
Nevertheless,mitochondrialdysfunction, even if it is a secondary event, might impact on the pathological processes.
From theCambridge English Corpus
Mitochondrialdysfunctionalso has important implications in cancer therapy.
From theCambridge English Corpus
Mitochondrialdysfunctionis a primary event in glutamate neurotoxicity.
From theCambridge English Corpus
Mitochondrialdysfunctionhas been found frequently as the basis of developmental defects.
From theCambridge English Corpus
They are thought to be a pathological hallmark ofmitochondrialdysfunction.
From theCambridge English Corpus
Glycogen depletion andmitochondrialdysfunctionwould, in combination, impair the ability of the cestode to repair tegument damage through reduced glycolysis and redox imbalance.
From theCambridge English Corpus
Mitochondrialdysfunctioncan also increase oxidative stress.
From theCambridge English Corpus
Where known, the protein products of these genes have been showed variously to be associated with abnormal protein accumulation and degradation, oxidative stress andmitochondrialdysfunction.
From theCambridge English Corpus
These data reflect severemitochondrialdysfunction.
From theCambridge English Corpus
Suggested causes have included channelopathy,mitochondrialdysfunction, and cerebrovascular dysfunction.
From
Wikipedia
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Furthermore, disruption of the yeast gene has been shown to result inmitochondrialdysfunction.
From
Wikipedia
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Common mechanisms include increased levels in oxidative stress,mitochondrialdysfunction, excitotoxicity, inflammatory changes, iron accumulation, and protein aggregation.
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Channel formation has been hypothesized to account for calcium dysregulation andmitochondrialdysfunction by allowing indiscriminate leakage of ions across cell membranes.
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Other inducers includemitochondrialdysfunction, oxidative stress, and abnormal protein aggregation.
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Membrane penetrating antioxidants have the most important role in improvingmitochondrialdysfunction.
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The putative mechanism of action is that manganese overexposure and/or dysregulation lead to oxidative stress,mitochondrialdysfunction, glutamate-mediated excitoxicity, and aggregation of proteins.
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In the brain this causes furthermitochondrialdysfunction, capillary leakage, leukocyte sequestration, and apoptosis.
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This condition is due tomitochondrialdysfunctionmediating the death of optic nerve fibers.
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Oxidative stress can directly cause neuron cell death or it can trigger a cascade of events that leads to protein misfolding, proteasomal malfunction,mitochondrialdysfunction, or glial cell activation.
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Prolonged permissive hypotension can lead to aggravated post-injury coagulopathy (coagulation dysfunction), ischemic damage secondary to poor tissue perfusion including the brain,mitochondrialdysfunction, and lactic acidosis among others.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
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Go to the definition ofmitochondrial
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See other collocations withdysfunction