mutant protein
collocation in Englishmeaningsofmutantandprotein
These words are often used together. Click on the links below to explore the meanings. Or,see other collocations withprotein.
mutant
noun[C]
uk/ˈmjuː.tənt/us/ˈmjuː.t̬ənt/
an organism that is different from others of its type because of a permanent change in ...
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protein
noun[C or U]
uk/ˈprəʊ.tiːn/us/ˈproʊ.tiːn/
one of the many substances found in food such as meat, cheese, fish, or eggs, that is necessary for the body to grow and ...
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(Definition ofmutantandproteinfrom theCambridge English Dictionary© Cambridge University Press)
Examplesofmutant protein
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
Molecular dynamics simulations of themutantproteinreveal that the region around the mutation assumes an alpha strand conformation.
From
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The small amount ofmutantproteinthat reached the cell membrane demonstrated diminished binding activity for neurexin-1, consistent with a loss of function.
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Wikipedia
Long before mutant proteins could be created in the laboratory, he had a large collection of single-site mutants of haemoglobin.
From theCambridge English Corpus
Similarly, when transfected into living epithelial cells, the mutant proteins behaved abnormally.
From theCambridge English Corpus
For this reason, the spectra of mutant proteins have to be evaluated very carefully.
From theCambridge English Corpus
The unstable or partially foldedmutantproteindoes not undergo trafficking and is usually rapidly degraded.
From theCambridge English Corpus
Themutantproteinlacks the cytoplasmic region, and is likely to be defective in signal transduction.
From theCambridge English Corpus
It is possible that the differences seen reflect the different genetic background of the families concerned, rather than functional differences in themutantproteinitself.
From theCambridge English Corpus
Themutantproteinwas unable to form intermediate filaments in vitro or intermediate filament networks in cultured muscle cells.
From theCambridge English Corpus
One possibility is that the chaperone capacity of a-crystallin is overwhelmed by the large amount ofmutantprotein.
From theCambridge English Corpus
This experiment suggests that removal or inactivation of themutantproteinmight be an effective therapeutic strategy, even after the onset of clinical disease.
From theCambridge English Corpus
However, in all cases, a significant proportion of themutantproteinformed disulphide-bonded dimers and higher molecular weight aggregates.
From theCambridge English Corpus
Perhaps substitution of the proline residue in themutantproteinresults in misfolding of the protein and degradation prior to insertion into the plasma membrane.
From theCambridge English Corpus
Therefore, one approach to promote folding of processing mutants would be to stabilise themutantprotein during the folding process through the use of chemical chaperones.
From theCambridge English Corpus
A mutation that leads to amutantproteinthat disrupts the activity of the wild-type protein in the multimer is a dominant-negative mutation.
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Wikipedia
P53 is a dominant negative mutation, so themutantproteincan inactivate the normal protein, meaning themutantproteinis dominant.
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Wikipedia
The mutant has been shown to cause defective neuroligin trafficking and retention of themutantproteinin the endoplasmic reticulum.
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Wikipedia
Mutantproteinantigens are likely to be much more specific to cancer cells because normal cells shouldn't contain these proteins.
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Wikipedia
When the trinucleotide repeat is present within the protein-coding region, the repeat expansion leads to production of amutantproteinwith gain of function.
From
Wikipedia
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
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