deleterious allele
collocation in Englishmeaningsofdeleteriousandallele
These words are often used together. Click on the links below to explore the meanings. Or,see other collocations withallele.
deleterious
adjective
uk/ˌdel.ɪˈtɪə.ri.əs/us/ˌdel.ɪˈtɪr.i.əs/
harmful:
See more atdeleterious
allele
noun[C]
uk/əˈliːl/us/əˈliːl/
a gene that is found in one of two or more different forms in the same position in a chromosome, and so produces a particular characteristic that can be different for different people, such as ...
See more atallele
(Definition ofdeleteriousandallelefrom theCambridge English Dictionary© Cambridge University Press)
Examplesofdeleterious allele
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
Fixation for a haplotype corresponds to fixation of adeleteriousalleleat a particular locus.
From theCambridge English Corpus
The loss of the least-loaded class is followed by the fixation of adeleteriousallelein the entire population.
From theCambridge English Corpus
In human populations, the gene of interest might be recessive, with genotypes only observable on individuals carrying two copies of thedeleteriousallele.
From theCambridge English Corpus
We can see immediately that the time taken to eliminate thedeleteriousalleleis not only dependent on the selection intensity, but also on the population structure.
From theCambridge English Corpus
Conversely, the lower fitness caused by having a less beneficial ordeleteriousalleleresults in this allele becoming rarer they are selected "against".
From
Wikipedia
Mutation-selection balance can be efficient in explaining the process of gene substitution only if one of these deleterious alleles acquires a relatively high selective advantage.
From theCambridge English Corpus
Here we study the effect of population size on the inbreeding depression caused by mildly deleterious alleles.
From theCambridge English Corpus
We found that the model has low statistical power when inbreeding depression is caused by the build-up of mildly deleterious alleles.
From theCambridge English Corpus
This might obscure the putative difference in fixation rates of slightly deleterious alleles.
From theCambridge English Corpus
We allowed the population to reach equilibrium, with regard to the frequency of deleterious alleles, with a fixed selfing rate.
From theCambridge English Corpus
Mutation to deleterious alleles is, therefore, probably not the sole source of the variation that underlies inbreeding depression.
From theCambridge English Corpus
The problem with mutation-selection balance is in the fact that it is based on deleterious alleles at very low frequencies.
From theCambridge English Corpus
More deleterious alleles can be concealed in those populations with larger additive genetic variance in fitness.
From theCambridge English Corpus
This suggests that a possible overall contribution of dominance would cause positive rather than negative skewness, resulting from dominance of deleterious alleles.
From theCambridge English Corpus
The model's poor detection of inbreeding effects therefore seems to have limited the detection of purging of mildly deleterious alleles.
From theCambridge English Corpus
Alternatively, the difference may reflect rapid purging of deleterious alleles in the first few generations of laboratory rearing.
From theCambridge English Corpus
Purging of deleterious alleles can also occur in species with a long history of inbreeding.
From theCambridge English Corpus
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
Want to learn more?
Go to the definition ofdeleterious
Go to the definition ofallele
See other collocations withallele