downstream target
collocation in Englishmeaningsofdownstreamandtarget
These words are often used together. Click on the links below to explore the meanings. Or,see other collocations withtarget.
downstream
adverb
adjective
uk/ˌdaʊnˈstriːm/us/ˌdaʊnˈstriːm/
in the direction a river or stream ...
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target
noun
uk/ˈtɑː.ɡɪt/us/ˈtɑːr.ɡɪt/
an object shot at during shooting practice, often a circle with a pattern of rings, or any object or place at which bullets, bombs, etc. ...
See more attarget
(Definition ofdownstreamandtargetfrom theCambridge English Dictionary© Cambridge University Press)
Examplesofdownstream target
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
We used multiple regressions where thedownstreamtargetis a predicted value and upstream splicing factors are predictor variables.
From theCambridge English Corpus
Thedownstreamtargetdelivers the snapshot to the next target, as in the push model.
From
Wikipedia
It influences cellular physiologic processes by regulating the expression ofdownstreamtargetgenes, which are related to growth, survival, and other cellular activities.
From
Wikipedia
In three-kinase signaling cascades, scaffolds bind all three kinases, enhancing kinase specificity and restricting signal amplification by limiting kinase phosphorylation to only onedownstreamtarget.
From
Wikipedia
Brn3a is a transcription factor which acts in development by regulatingdownstreamtargetgenes.
From
Wikipedia
This observation could suggest that these genes are downstream targets of the genetic changes that cause hybrid male sterility in these species.
From theCambridge English Corpus
However, the phosphorylation o f some downstream targets occurs in a phosphoinositide-dependent manner through modificati on of its substrates.
From theCambridge English Corpus
The mechanism for this failure is not clear but is likely to involve dysregulation of downstream targets.
From theCambridge English Corpus
However, it is unknown whether a 2-fold or 10-fold reduction in its expression would necessarily cause underexpression of its downstream targets or sterility.
From theCambridge English Corpus
Nutrition-sensitive hypothalamic neuropeptides are the most prominent downstream targets of leptin.
From theCambridge English Corpus
It is clear that matrix-degrading proteases are essential for tumour progression, but it is not known whether they all act in independent pathways or have some common downstream targets.
From theCambridge English Corpus
Downstream targets of this pathway are upregulated and these ensure the transition to the second phase.
From theCambridge English Corpus
Its activation mechanism and downstream targets are still not well characterized.
From
Wikipedia
They help stabilize catenin, which activates downstream targets.
From
Wikipedia
Once they occur as duplicates, accumulated mutations encoding for one copy can take place without negatively affecting the regulation of downstream targets.
From
Wikipedia
These kinases phosphorylate downstream targets in a signal transduction cascade, eventually leading to cell cycle arrest.
From
Wikipedia
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
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