epigenetic alteration

collocation in English

meaningsofalteration

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alteration
noun
uk
/ˌɒl.təˈreɪ.ʃən/us
/ˌɑːl.t̬əˈreɪ.ʃən/
a change, usually a slight change, in the appearance, character, or structure ...
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(Definition ofalterationfrom theCambridge English Dictionary© Cambridge University Press)

Examplesofepigenetic alteration

These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
Patients can be divided into subgroups with particular cytogenetic, molecular genetic or epigenetic alterations.
From theCambridge English Corpus
In addition to genetic changes, epigenetic alterations including methylation or imprinting could also lead to the somatic inactivation of candidate tumour suppressor genes.
From theCambridge English Corpus
Such field defects (second level from bottom of figure) may have multiple mutations and epigenetic alterations.
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Such mutations and epigenetic alterations can give rise to cancer (see malignant neoplasms).
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However, it has become apparent that cancer is also driven by epigenetic alterations.
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Mutations, however, may not be as frequent in cancers as epigenetic alterations.
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These errors can give rise to mutations or epigenetic alterations.
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However, by comparison, epigenetic alterations in colon cancers are frequent and affect hundreds of genes.
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It would also be expected that many of the epigenetic alterations present in tumors may have occurred in pre-neoplastic field defects.
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Likewise, epigenetic alterations present in tumors may have occurred in pre-neoplastic field defects.
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Epigenetic alterations refer to functionally relevant modifications to the genome that do not involve a change in the nucleotide sequence.
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Inadequate uterine receptivity may be caused by abnormal cytokine and hormonal signaling as well as epigenetic alterations.
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Once substance use commences, however, epigenetic alterations may further exacerbate the biological and behavioural changes associated with addiction.
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Epigenetic alterations are reversible meaning that they can be targets for therapy.
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Epigenetic alterations of gene regulation or phenotype generation that are subsequently consolidated by changes at the gene level constitute another class of mechanisms for evolutionary innovation.
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Epigenetic alterations occur frequently in cancers.
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These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
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