| 单词 | proteasome |
| 释义 | BETA Examples ofproteasomeDictionary> Examples ofproteasome proteasomeisn’t in the Cambridge Dictionary yet. You can help! Add a definition Protofibrils may promote their own accumulation and toxicity by inhibiting theproteasome. From theCambridge English Corpus If redistribution ofproteasomecomponents into inclusions depletes the neuron of functional proteolytic activity, the results could be deleterious. From theCambridge English Corpus The ubiquitin andproteasomelocalizations in this process are also reported here. From theCambridge English Corpus Ubiquitination andproteasomemediated degradation of polo-like kinase. From theCambridge English Corpus Ubiquitin was seen to form a ring around the pronucleus, whereasproteasomewas evenly distributed in the pronuclear region. From theCambridge English Corpus The possible substrates ofproteasomein and around the pronucleus and their significance remain to be determined in further studies. From theCambridge English Corpus Inducible expression of mutant alpha-synuclein decreasesproteasomeactivity and increases sensitivity to mitochondria-dependent apoptosis. From theCambridge English Corpus One potentially useful class of new drugs are theproteasomeinhibitors. From theCambridge English Corpus A major role of theproteasomeis to degrade short-lived proteins, including some transcription factors. From theCambridge English Corpus Looking ahead to therapeutic implications, identification and use of factors that would permit normalproteasomeand autophagosome functions are an interesting possibility. From theCambridge English Corpus In this study, the role ofproteasomein the spontaneous and parthenogenetic activation of rat oocytes was investigated. From theCambridge English Corpus It is also interesting to note that the maintenance of the protrusion needs the activity ofproteasome. From theCambridge English Corpus Impairment of the ubiquitin-proteasomesystem causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures. From theCambridge English Corpus They are formed in response to cellular overload of misfolded proteins after the ubiquitin -proteasomesystem and the unfolded-protein response become overwhelmed. From theCambridge English Corpus This unknown protein prevents cytokinesis if the oocyte lacks the activity ofproteasome, which is also a prerequisite for nuclear division. From theCambridge English Corpus These experiments raise the possibility thatproteasomeactivity is regulated by calcium. From theCambridge English Corpus Reductionist in vitro studies suggest that the amyloid protofibril may be the toxic species and that it may amplify itself by inhibitingproteasome-dependent protein degradation. From theCambridge English Corpus These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. |
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