Powder for oral suspension contains sucrose and should not be used in patients with hereditary fructose, glucose/galactose malabsorption orsucrase-isomaltase deficiency.
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Other brush border enzymes are maltase,sucraseand lactase.
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Invertase is asucraseused industrially for the hydrolysis of sucrose to so-called invert sugar.
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Sucraseis secreted by the tips of the villi of the epithelium in the small intestine.
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Sucraseis an enzyme that breaks down the disaccharide sucrose, commonly known as table sugar, cane sugar, or beet sugar.
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As with other sugars, sucrose is digested into its components via the enzymesucraseto glucose (blood sugar) and fructose.
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In the small intestine, this enzyme works in synergy withsucrase-isomaltase and alpha-amylase to digest the full range of dietary starches.
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If the enzymesucraseis added, however, the reaction will proceed rapidly.
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Sucrose is broken down during digestion into a mixture of 50% fructose and 50% glucose through hydrolysis by the enzymesucrase.
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In most cases, sucrose intolerance is an autosomal recessive, genetic, metabolic disease, and involves deficiency in the enzymesucrase, which breaks apart the glucose and fructose molecules.
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Sucrose intolerance ("congenitalsucrase-isomaltase enzyme deficiency") can be caused by genetic mutations in which both parents must contain this gene in order for the child to carry the disease.
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