Smallpox and cowpox are closely allied and the substances formed in the blood by the one are resistant to the virus of the other.
The disease becomes modified when transferred to cattle, producing what is known as cowpox, in which vesicles similar to those of smallpox appear on the skin.
The germ of cowpox, which is believed to be either the cow or horse variety of human smallpox, is cultivated upon healthy calves.
Examplesofcowpox
cowpox
Prior to admission, all children were given acowpoxvaccination to prevent smallpox and the orphanages employed a doctor who provided the necessary medical care.
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Viral inhibition of inflammation :cowpoxvirus encodes an inhibitor of the interleukin-1 beta converting enzyme.
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A total of five deaths fromcowpoxand post-vaccinal complications were registered during the period, one in 1948, two in 1950, and two in 1951.
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He attempted to maintain a monopoly over thecowpoxvaccine, for both financial reasons and to protect the vaccine from incompetent or fraudulent physicians.
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He usedcowpoxto confer induced immunity on humans.
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Scientists have not determined exactly when the change or mutation occurred, but the effects of vaccinia andcowpoxvirus as vaccine are nearly the same.
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Jenner was not the first person to inoculate withcowpoxnor the first to realize that infection withcowpoxgave immunity to smallpox.
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Other vaccine material was not reliably derived fromcowpox, but from other skin eruptions of cattle.
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At some point, the virus in use was no longercowpox, but vaccinia.
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Immunity tocowpoxis gained when the smallpox vaccine is administered.
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Vaccinia,cowpox, and monkeypox viruses can infect both humans and other animals in nature.
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Cowpoxis a poxvirus in the same family as variola.
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This confirmed his childhood suspicion, and he studiedcowpoxfurther, presenting a paper on it to his local medical society.
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Cowpoxis similar to, but much milder than, the highly contagious and often deadly smallpox disease.
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He deduced thatcowpoxwas most likely to transfer immunity from smallpox if administered at the eighth day of the disease.
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