epigenetic modification
collocation in Englishmeaningsofmodification
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modification
noun
uk/ˌmɒd.ɪ.fɪˈkeɪ.ʃən/us/ˌmɑː.də.fəˈkeɪ.ʃən/
a change to something, usually to ...
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(Definition ofmodificationfrom theCambridge English Dictionary© Cambridge University Press)
Examplesofepigenetic modification
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Recent evidence also suggests thatepigeneticmodificationof gene expression may be a key factor and that this has the potential to produce transgenerational effects.
From theCambridge English Corpus
As with many examples ofepigeneticmodification, ' reversions ' occur sporadically that restore the standard phenotype.
From theCambridge English Corpus
Regions of parental-allele-specificepigeneticmodificationsuch as this are associated with genes regulated by genomic imprinting and expressed from only one parental chromosome.
From theCambridge English Corpus
However, these effects are also likely to involveepigeneticmodificationof the genome.
From theCambridge English Corpus
Another cause of difference between monozygotic twins isepigeneticmodification, caused by differing environmental influences throughout their lives.
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This can lead to histone modification and, if furtherepigeneticmodificationoccurs, heterochromatin formation.
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These findings provide evidence thatepigeneticmodificationin the prefrontal lobe is a risk factor for bipolar disorder.
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Though hundreds of examples ofepigeneticmodificationof phenotypes have been published, few studies have been conducted outside of the laboratory setting.
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Thisepigeneticmodificationis triggered by environmental events.
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Various genetic sequences can be targeted forepigeneticmodification.
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Editing epigenomic features in this manner allows researchers to determine the exact biological role of anepigeneticmodificationat the site in question.
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Studies have suggested other signalling pathways that could affect epigenetic modifications and therefore provide suitable therapeutic targets.
From theCambridge English Corpus
Epigenetic modifications during oocyte growth correlates with extended parthenogenetic development in the mouse.
From theCambridge English Corpus
It has been shown that epigenetic modifications can also regulate telomere length through the modulation of the chromatin environment of the telomeres themselves.
From theCambridge English Corpus
In vitro fertilization causes epigenetic modifications to the onset of gene expression from the zygotic genome in mice.
From theCambridge English Corpus
Here we examine the human orthologues of mouse genes imprinted only in the placenta, assaying allele-specific expression and epigenetic modifications.
From theCambridge English Corpus
In mature oligodendrocytes, the expression of inhibitory molecules is silenced by additional epigenetic modifications, including histone methylation and chromatin compaction.
From theCambridge English Corpus
Data establishing epigenetic processes as important regulators of senescence and tumourigenesis also suggest that such epigenetic modifications may be useful as prognostic markers.
From theCambridge English Corpus
Environmental cues, including dietary components, present in the in utero environment can induce significant changes in the expression of the genome through epigenetic modifications.
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Therefore, epigenetic modifications may account for some of the behavioural changes generally associated with addiction.
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These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
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