leptin resistance

collocation in English

meaningsofleptinandresistance

These words are often used together. Click on the links below to explore the meanings. Or,see other collocations withresistance.
leptin
noun[U]
uk
/ˈlep.tɪn/us
/ˈlep.tɪn/
a hormone (= a chemical made in the body) that controls feelings of hunger and the way the body ...
See more atleptin
resistance
noun
uk
/rɪˈzɪs.təns/us
/rɪˈzɪs.təns/
the act of fighting against something that is attacking you, or refusing to ...
See more atresistance

(Definition ofleptinandresistancefrom theCambridge English Dictionary© Cambridge University Press)

Examplesofleptin resistance

These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
Therefore, agerelatedleptinresistancemay be caused by increased adiposity or prolonged exposure to the elevated leptin, or both.
From theCambridge English Corpus
There are several possible mechanisms for ageassociatedleptinresistance, including alterations in leptin-accessibility to the central nervous system and hypothalamic response to leptin during aging.
From theCambridge English Corpus
Another possibly effective approach that could overcome age-relatedleptinresistanceis the activation of signalling pathways downstream of the hypothalamic leptin receptors.
From theCambridge English Corpus
It is still unknown whether lifelong exercise can prevent the development ofleptinresistanceduring aging.
From theCambridge English Corpus
Some evidence suggests that prolonged exposure to the elevated level of leptin may play a causative role in agerelatedleptinresistance.
From theCambridge English Corpus
The role ofleptinresistancein the lipid abnormalities of aging.
From theCambridge English Corpus
Thus, approaches that could reverse or preventleptinresistancewould be attractive candidates.
From theCambridge English Corpus
Collectively, aging is associated withleptinresistance, and reduced sensitivity to leptin occurs in middle age.
From theCambridge English Corpus
When low birthweight offspring are permitted rapid catch-up growth by nutrient availability, these offspring will demonstrate evidence of increased body weight and body fat, andleptinresistanceas adults.
From theCambridge English Corpus
Impairments in leptin sensitivity (leptinresistance) become evident at relatively early age (by middle age) in parallel with age-associated elevation in leptin in rodents.
From theCambridge English Corpus
Aging is clearly associated withleptinresistancethat could play a causative role in age-associated neuroendocrine and metabolic impairments.
From theCambridge English Corpus
The changes that occur in the hypothalamus to result inleptinresistancein obesity are currently the focus of obesity research.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
Holtorf treatsleptinresistancein patients with a class of medications that are typically reserved for controlling blood sugar levels in diabetics.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
These knock-out mice were hyperphagic which led to obesity, partialleptinresistance, increased adipose deposition, insulin resistance and impaired glucose tolerance.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
Suchleptinresistancemay translate into diseases, notably it could be responsible for obesity in humans who have high levels of leptin.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
Leptinresistanceplays a role in the process where appetite overrules the message of satiety.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
Leptinresistancecan be triggered in rats by ad libitum consumption of energy-dense, highly palatable foods over a period of several days.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
Yet another proposed mechanism involves the phenomenon known asleptinresistance.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
He demonstrated that human obesity is not characterized by leptin deficiency but byleptinresistance and helped usher in leptinomania in the study of obesity.
From
Wikipedia
This example is from Wikipedia and may be reused under a CC BY-SA license.
These examples are from corpora and from sources on the web. Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors.
Want to learn more?
Go to the definition ofleptin
Go to the definition ofresistance
See other collocations withresistance